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Posters with an odd number will be presented during Poster Session 1 (Tuesday, 17 June, 17:00-18:30). Posters with an even number will be presented during Poster Session 2 (Wednesday, 18 June, 10:30-12:00).

P.1 Natalia Abate, Naples
Impaired Chaperonin TRiC/CCT complex in Neurodevelopmental Disorders: new insights into EPM1 disease

P.2 Diana Marisol Abrego Guandique, Catanzaro
Conserved milk-derived miRNAs and their role in immune modulation 

P.3 Martina Addeo, Naples
Bridging bench to bedside: natural therapies for preeclampsia assessed in complementary experimental models

P.4 Antonella Altieri, Naples
Identification of potential biomarkers from epileptic lesions in FFPE samples by using proteomics approaches

P.5 Susanna Ambrosio, Naples
Exploring Lamin's role in genomic stability and DNA repair

P.6 Fabrizia Ametrano, Naples
Modeling fructose-induced brain alterations: integrating in vivo and stem cell-based in vitro systems

P.7 Filomena Amoroso, Naples
Investigating the epigenetic control of 3D gastruloid development using Epi-drugs

P.8 Ylenia Antonacci, Bari
TRIM8: a key player in chemosensitivity recovery of cancer cells

P.9 Dario Balestra, Ferrara
Base and Prime editing to revert Hemophilia A-causing point mutations

P.10 Chiara Barone, Naples
MiR-204 is required for photoreceptor rod differentiation and maturation

P.11 Rafael Battisti Cavichion, Trento
Modulation of exosome content by cell line engineering for the treatment of metastatic prostate cancer

P.12 Giorgia Lucia Benedetto, Cosenza
Q-VD-OPh-mediated caspase inhibition rescues pathological phenotype in sporadic Parkinson’s Disease dopaminergic neurons via PKA-CREB pathway activation

P.13 Matteo Bertoli, Brescia
ADAR therapy: a breakthrough against genetic disorders

P.14 Elena Bianchi, Pavia
Discovery of Ellagitannins as new potent and selective SGK1 inhibitors

P.15 Laura Bottoni, Siena
NRF2 activation by cysteine as a survival mechanism in TNBC

P.16 Guglielmo Bove, Naples
Virma as a vulnerable target in leukemia

P.17 Alessio Branchini, Ferrara
Recoding of premature termination codons by engineered tRNAs to rescue protein biosynthesis and function in hemophilia models

P.18 Gaja Bruno, San Giovanni Rotondo, FG
Genetic inactivation of EZH2 histone methyltransferase cooperates with HOXA9 oncogene to drive T-cell transformation and defines a distinct subtype of human T-ALL

P.19 Noemi Cabella, Pavia
Novel insights into the role of miRNA hsa-miR-1307-3p in DNA-RNA hybrids metabolism

P.20 Vincenza Capo, Naples
HAT1 as a potential oncogenic factor in breast cancer: implications for tumor progression and therapeutic targeting

P.21 Alessio Capone, Rome
TrkB is a potential therapeutic target for invasive cutaneous squamous cell carcinoma

P.22 Roberta Capuana, Pozzuoli
Analysis of microbiome in Inflammatory Bowel Diseases (IBDs) and Irritable Bowel Syndrome (IBS) in pediatric patients

P.23 Davide Capuano, Bari
Correcting G>A point mutations causing fALS by Site-directed RNA editing

P.24 Daniela Carannante, Naples
Epigenetic modulation of netosis: insights into cell death mechanisms

P.25 Iolanda Carratu', Naples
Mitochondrial disruption in Ezrin^-/- models related to apoptotic cell death  

P.26 Chiara Centrella, Fisciano, SA
Toward an in vitro model of gastric intestinal metaplasia using human gastric organoids and mucosoids

P.27 Mario Chiariello, Siena
MAPK15 controls intracellular lipid uptake and protects mammalian liver from steatotic disease

P.28 Martina Coco, Turin
miR-148b induces mitochondrial dysfunction and inhibits melanoma progression

P.29 Ivan Conte, Naples
Targeting glucose metabolism improves retinal phenotype in CHM medaka model

P.30 Arianna Coppola, Naples
Long non-coding RNA T-UCstem1 modulates paracrine WNT signaling during gastruloid morphogenesis

P.31 Susan Costantini, Naples
Evaluation of the effects of VCP inhibitors in cellular cancer models by an integrated analysis of the expression of endoplasmic reticulum stress-associated genes and metabolomics profiling

P.32 Raffaele Covello, Cosenza
TAU pathology and axonal injury are hallmarks of sporadic progressive supranuclear palsy disease in induced pluripotent stem cell-derived dopaminergic neurons

P.33 Sharon Cox, Bari
MitSorter: a standalone to discriminate mtDNA and NuMT ONT reads based on differential methylation for more accurate variant calling

P.34 Flora Cozzolino, Naples
Effects of growth conditions on phosphorylation level of CDKL5 in antarctic bacterial Pseudoalteromonas haloplanktis TAC 125

P.35 Marco Cristiano, Naples
A bottom-up approach to engineering the 3D fibrotic microenvironment in pancreatic ductal adenocarcinoma

P.36 Emilio Cusanelli, Trento
Investigating the role of TERRA in telomere maintenance mechanisms and therapy response of cancer cells

P.37 Massimo D'Agostino, Naples
A light-resuming strategy as a new screening method for Sec61 inhibitors: discovery of small molecules down-modulating PD-L1 expression

P.38 Davide D'Onghia, Novara
Macrophage polarization and CEBP factors functional interplay

P.39 Carola De Martinis, Verona
Editing RUNX2 KO in B16 melanoma cells with Crispr-Cas9  as a potential strategy to enhance in vivo tumor response to therapeutic approaches

P.40 Vito De Pinto, Catania
Peptide-coding mRNA (ppNA) to win Neurodegenerative Diseases (NDD) and cancer

P.41 Rosa De Santis, Pozzuoli
Reprogramming-to-organoids: how to cost-efficiently leverage hIPSCs to model human diseases

P.42 Filomena Del Piano, Naples
Lipid nanoparticles as in vitro and in vivo delivery strategy for direct cell reprogramming into dopamine neurons

P.43 Valentina Di Francesco, Rome
Functional genomics in psoriasis: correlation between the presence of single nucleotide polymorphisms or haplotypes in the HLA-C gene upstream region and biogenesis of regulatory long non-coding RNAs

P.44 Serena di Iasio, San Giovanni Rotondo, FG
Development of antigen-specific CAR-T cells targeting leukemic initiating cells in human T-cell acute lymphoblastic leukemia

P.45 Elena Di Nisio, Rome
SCF^Fbxo22 complex regulates KDM5B stability, potentially influencing the epigenetic landscape in breast cancer

P.46 Annalisa Di Ruscio, Boston, USA
Predicting DiR signature in myelodysplastic syndromes by MOIRA an AI driven Multi-Omics Integration Research Assistant

P.47 Daniele Durante, Rome
Understanding determinants and functions of MATR3 binding along HSCHARME intronic sequence

P.48 Federico Pio Fabrizio, San Giovanni Rotondo, FG
Epigenetic alterations of SPARC in idiopathic pulmonary fibrosis: insights from an explorative study

P.49 Irene Farabella, Genoa
Walking along an entire human chromosome at the nanoscale

P.50 Maddalena Fenech, Naples
Generation of a GD2 ganglioside-targeted H. simplex vector for oncolytic virotherapy

P.52 Alessia Fornaro, Naples
Targeting LAT1 to modulate boron uptake in osteosarcoma: implications for BNCT

P.53 Silvia Fortuni, Pomezia, RM
A platform for comprehensive CRISPR/Cas9 genome editing in preclinical research and drug discovery

P.54 Bruno Fosso, Bari
Reliable and Effective taxonomic classification of MAGs with kMetaShot

P.55 Rachele Frigerio, Catanzaro
Novel oncomiRs released in melanoma extracellular vesicles (EVs) drive resistance to immunotherapy by modulating intercellular networks that promote melanoma immune evasion

P.56 Petronilla Frugis, Bari
Correcting a pathogenic G>A point mutation in SBF1 gene by Site-directed RNA editing

P.57 Tonya Fusco, Naples
STEPS: a novel approach to dissect the genetic bases of Hereditary Breast and Ovarian Cancer

P.58 Michele Galluccio, Rende, CS
The transcriptional response of the SNAT2 transporter gene to amino acid starvation

P.59 Gennaro Gandolfo, Pozzuoli
Dissecting the functional effects of BRCA1 perturbations in HBOC syndrome via deep mutational scanning

P.60 Armando Gisonna, Naples
Celecoxib activates a ROS-mediated mitochondrial apoptotic program in 2D and 3D melanoma cell cultures

P.61 Antonio Grimaldi, Pozzuoli
Deciphering molecular patterns in pediatric IBDs and FGIDs through a multi-omics framework

P.62 Ilaria Grossi, Brescia
Molecular profiling of tissue and circulating cancer-related ncRNAs in hepatocellular carcinoma

P.63 Francesca Guarino, Catania
Comprehensive DNA methylation landscape of the VDAC1 gene: insights into promoter, intronic, and intergenic regulatory elements

P.64 Ciro Iaccarino, Sassari
Cyanobacterial toxins induce protein aggregation and autophagy dysregulation in Parkinson's and ALS disease models

P.65 Ilaria Iacobucci, Naples
Hijacking the host: SARS-CoV-2 Spike S exploits tumor-like strategies to invade and rewire host cells

P.66 Olimpia Iacolare, Naples
Paxilllin plays a critical role in the pharyngeal archs segmentation during the pharyngeal apparatus morphogenesis

P.67 Marta Ianni, Naples
Cell-non-autonomous phenotype in EPM1 pathogenesis can be modulated by EVs-derived microRNAs

P.68 Maria Roberta Iazzetta, Caserta
Identification of novel regulatory network controlling human dopaminergic neuron specification and protection

P.69 Iolanda Infantino, Catania
Mitochondrial TSPO overactivation is linked to impaired respiration and mitophagy in a mouse model of ALS

P.70 Hulyam Kurt, Eskisehir, Turkey
Biomarker potential of the pyroptosis protein gasdermin D for prostate cancer

P.71 Luca La Via, Brescia
Functional impact of CYFIP2 RNA Editing on actin regulation, axon growth, and spinogenesis

P.72 Pietro Laneve, Rome
The MYC-dependent lncRNA MB3 inhibits apoptosis in Group 3 Medulloblastoma by regulating the TGF-β pathway via HMGN5

P.73 Ida Lazzinnaro, Catanzaro
Analysis of mitochondrial dysfunction in a human iPSC-derived organoid model of progressive supranuclear palsy

P.74 Manuela Leo, Benevento
PPARγ interaction with oleacein and oleocanthal mediates the enhanced mitochondrial activity and antioxidant response in colorectal cancer cells

P.75 Domenico Liguoro, Rome
miR-579-3p as a checkpoint for adaptation to target therapy in melanoma

P.76 Camilla Lodola, Pavia
Targeting the SARS-CoV-2 nucleocapsid–DDX3X interaction: domain mapping and inhibitor screening

P.77 Erika Lorusso, Bari
Assessment of gut microbiome eubiosis/dysbiosis based on DNA metabarcoding data by using machine learning approaches

P.78 Vincenzo Lullo, Naples
Gene correction in ICF patient-derived iPSCs restores DNA methylation and hematopoietic potential

P.79 Matteo Marchetti, Naples
A native promoter-based toolkit to tune gene expression in engineered macrophages

P.80 Caterina Margheriti, Turin
Characterization of transcriptional networks as possible molecular targets in basal-like breast cancer

P.81 Stefania Martucciello, Fisciano, SA
Tbx1-Vegfr3 interaction is required in cardiac morphogenesis

P.82 Flaviana Marzano, Bari
Plasma membrane amino acid transporters and VDACs in the metabolic rewiring of glioblastoma: from multi-omic approaches to targeted treatment

P.83 Simone Mas, Palermo
A mechanobiological approach to study PDAC progression and pharmacological response

P.84 Mirella Massa, Pozzuoli
Dissecting CDKL5 deficiency disorder through functional genomics approaches

P.85 Alessia Mavillonio, Trento
Optimizing the delivery of chemically modified antisense oligonucleotides and siRNAs: moving towards clinical use of RNA therapeutics for neurodevelopmental disorders

P.86 Elisabetta Meacci, Florence
Modulation of myofibroblasts by PC3-released factors: a role for RNA technology-based sphingosine 1-phosphate-mediated signaling

P.87 Mirko Meneghel, Verona
Investigating differential migration of healthy osteoblasts and osteosarcoma cells

P.88 Giacomo Menichetti, Verona
Ribonucleoprotein RBM20 expression is upregulated during neuroblastoma SH-SY5Y cell line differentiation and correlates with Tau exon 10 and Tau exon 6 inclusion

P.89 Maria Rosaria Mentino, Naples
Combining Proteomics and Bioinformatics to identify breast cancer biomarkers binding telomeric G-Quadruplex

P.90 Claudia Moriello, Naples
Targeting senescent mesenchymal stromal cells: SRC kinase inhibitors as promising senotherapeutic agents

P.91 Luciano Mottola, Pozzuoli
A molecular approach with antisense oligonucleotides (ASOs) for ultra-rare genetic disorders

P.92 Alessandro Nasti, Kanazawa, Japan
Eight-year longitudinal whole blood transcriptomic analysis allows to distinguish between the ageing-related gene expression variations, and the inflammation/metabolic dysregulations correlated to the declining insulinogenic index

P.93 Michela Palmieri, Milan
Unraveling autophagic proteins in synaptosomes of developing brains

P.94 Sara Palumbo, Naples
Talazoparib triggers irreversible cell death in cSCC: a preclinical therapeutic perspective

P.95 Xena Giada Pappalardo, Catania
Study of the recruitment of putative regulatory elements of the pseudogene VDAC1P8 by bioinformatic approach

P.96 Chiara Papulino, Naples
LAT1 as a therapeutic lever in BNCT: implications of epigenetic regulation and siRNA silencing in osteosarcoma

P.97 Deanira Patrone, Naples
Multilineage-differentiating stress-enduring (MUSE) cells as an innovative in vitro model for psychotic and mood disorders

P.98 Valerio Perticaroli, Rome
Crosstalk between CPEB1 and miR-135 family members

P.99 Vittoria Petruzzella, Bari
mTOR/AKT signalling as a molecular target in mitochondrial-related peripheral neuropathies

P.100 Stefano Pezzini, Milan
Overcoming premature termination codons in  neurodevelopmental diseases with anticodon-engineered tRNAs

P.101 Mariaceleste Pezzullo, Caserta
Unveiling the oncogenic role of RacGAP1 in lung adenocarcinoma by Wnt/β-catenin pathway regulation

P.102 Miriam Piccioni, Naples
The cross-kingdom activity of plant miRNAs as novel therapeutic tools in human diseases

P.103 Anna Piscone, Naples
Unravelling the impact of the base excision repair deficiency to genomic instability and inflammation

P.104 Valeria Poli, Turin
Guilty by association: calcium-mediated apoptosis regulated at the ER by a newly discovered mTOR-STAT3 pathway

P.105 Giovanna Ponticelli, Naples
Generation and characterization of lung organoids from human pluripotent stem cells to tackle lung fibrosis

P.106 Sara Pozzi, Milan
Unraveling p53 dynamics in colorectal cancer: a key to understanding chemotherapy resistance?

P.107 Monica Procacci, Bologna
Proteome diversity predicts functional differences of micronuclei in human cancer cells

P.108 Valentina Proserpio, Turin
The vulvar ecosystem: microbiome composition and the mutual crosstalk with host cells

P.109 Carmela Ramondino, Rome
Functional validation of a novel ATM variant in a patient with multiple melanoma: implications for personalized prevention and treatment

P.110 Alberto Raoss, Trento
Restoring physiological PMP22 expression in CMT1A cellular models via base editing of the Kozak sequence

P.111 Simona Reina, Catania
Investigation of VDAC3 gene expression regulation by oxidative stress

P.112 Jonathan Fernando Reinoso Sánchez, Rome
Histone deacetylase 3 displays anti-fibrotic activity in recessive dystrophic epidermolysis bullosa

P.113 Davide Rizzini, Trento
Understanding C9orf72 intron 1 retention in ALS to design therapeutic antisense oligonucleotides

P.114 Sabrina Rizzolio, Turin
miR-214 as a therapeutic target in BRAF inhibitor-resistant malignant melanomas

P.115 Maria Lorenza Rusciano, Naples
Exploring the pancreatic-like cell composition of a sea urchin at the single-cell resolution

P.116 Marco Russo, Bologna
Topoisomerase 1 poisoning-dependent mutational signatures in colorectal cancer

P.117 Michele Sallese, Chieti
Structural and functional analysis of the novel pathological variant c.1024G>A in the SIL1 gene causing Marinesco-Sjögren syndrome

P.118 Marcello Salvi, Pozzuoli
Integrative genomics reveals FGFR4 mutations and TGFβ-driven immune escape in cancer of unknown primary

P.119 Afshin Samiminemati, Naples
Mitochondrial microproteins in cellular stress: the multifaceted role of humanin

P.120 Luca Sanna, Rome
Extracellular NAMPT promotes keratinocyte hyperproliferation and inflammation via TLR4/TLR2 pathways and contributes to psoriasis symptoms in an Imiquimod-Induced mouse model

P.121 Martina Santulli, Bologna
Dissecting the function of PRR12 and its role in Neuroocular Syndrome through a multi-omic approach

P.122 Andrea Scircoli, Turin
MiR-214 drives metabolism rewiring in melanoma by regulating proteins involved in the endoplasmic reticulum-mitochondria axis

P.123 Mohd Shahzaib, Naples
Decoding cellular senescence: a meta-analysis of transcriptomic networks and key molecular drivers

P.124 Domenico Alessandro Silvestris, Bari
Recoding RNA editing as a source of tumor-specific neoantigens in pancreatic neuroendocrine tumors

P.125 Marco Simula, Rome
Dissecting the role of tissue-specific lncRNAs in muscle-nerve interaction using human neuromuscular organoids

P.126 Jahnavi Srivatsa, Turin
STAT3-siRNA-aptamer chimeras to target tumour-stroma crosstalk in breast cancer

P.127 Eleonora Stanca, Lecce
Concentrated growth factor induces ER stress and apoptosis by increasing ceramide generation in selected tumor cell lines

P.128 Maria Letizia Taddei, Florence
PHGDH expression modulates arachidonic acid pathway and 5-FU resistance in colorectal cancer

P.129 Nadia Tagliaferri, Pavia
Cisplatin adducts repair is imbalanced in CANVAS B-Lymphoblastoid cell lines

P.130 Mariagrazia Talarico, Catanzaro
Decoding sporadic PSP-RS: MAPK/ERK and PI3K/Akt pathways as central disease drivers

P.131 Federico Tolino, Novara
Exploring the molecular mechanisms of early-onset breast cancer

P.132 Paola Tucci, Rende, CS
Molecular insights into curcumin’s TLR4 inhibition in TNBC: hyperglycemia as a critical regulator

P.133 Didem Turgut Cosan, Eskisehir, Turkey
Altered breast cancer cell death associated with KCNA3 and/or EAG1 silencing through voltage-gated potassium channels (VGPCs)

P.134 Chantal Usai, Genoa
Improve accessibility of Chromatin Tracing experiments 

P.135 Lorenzo Vaccaro, Pozzuoli
Genotype-phenotype single-cell transcriptomics for massive parallel assessment of genetic variants

P.136 Danila Valletta, Caserta
Characterization of miR-125a targetome in human hepatocarcinoma cells

P.137 Anna Vareschi, Verona
Activity of a methyl-ester sulphonate detergent combined with silver-derivatized magnetic nanoparticles

P.138 Angelo Sante Varvara, Bari
Comparative evaluation of long and short-read sequencing technologies for human trio genotyping

P.139 Giulia Verrilli, Ariano Irpino
Pro-apoptotic activity of polyphenol-rich extract from Camellia japonica flowers in leukemia cell lines

P.140 Mauro Voi, Verona
A precise characterisation of peptide binding stability to HLA-C alleles and correlation with the progression of HIV-1 infection and HIV-1 related neurocognitive impairment

P.141 Muhammad Waqas, Naples
CBX3 as a prognostic biomarker in lung cancer

P.142 Jan Zamporlini, Milan
LINE1 maintain T-cell resting state by regulating ribosome biogenesis and chromatin organization through phase-separated nuclear condensates

P.143 Giorgia Zappacosta, Povo, TN
Friedreich's Ataxia: increased of expression of frataxin levels by genomic editing and generation of 3D in vitro cellular models with iPSCs